|
 | PI Name: | PATRICK BARTA, M.D., PhD | |
| PI Name: | NANCY HONEYCUTT, PhD | ||
| DEPARTMENT OF PSYCHIATRY AND BEHAVIORAL SCIENCES JOHNS HOPKINS UNIVERSITY, SCHOOL OF MEDICINE BALTIMORE, MD | |||
| PI Name: | GODFREY PEARLSON, M.D. | ||
| CLINICAL COGNITIVE NEUROSCIENCE LABORATORY THE INSTITUTE OF LIVING, HARTFORD HOSPITAL HARTFORD, CT | |||
| Project Title: | AUDITORY HALLUNICATION IN SCHIZOPHRENIA |
Abstract:
The planum temporale (PT) has been of interest because of (1) its consistent left greater than right asymmetry
among right-handed and most left-handed normal individuals; and (2) its relation to language, another variable
shown to be highly left-lateralized in normal subjects. Individuals with neurodevelopmental disorders have been
reported to show abnormal PT asymmetry (either reversed or absent asymmetry). Several studies have been conducted
measuring the PT on MRI scans, although the results do not always concur. We review some of these studies and discuss
methodological differences between them. Additionally, we propose a method that has proved to be highly reliable for
the measurement of both temporal PT and its parietal extension (PT+).
References:
Honeycutt
NA, Musick A, Barta PE, Pearlson GD:
Measurement of the planum temporale (PT) on magnetic resonance imaging scans: temporal PT alone and with parietal extension.
Psychiatry Res 2000 Apr 10;98(2):103-16.
Links:
Clinical Cognitive Neuroscience Laboratory, The Institute of Living, Hartford Hospital
Division of Psychiatric Neuro-Imaging, Department of Psychiatric Neuro-Imaging, Johns Hopkins University School of Medicine
Brain Subvolume Image Data for Validation of Segmentation
20 subvolumes(10 each of left and right) are available in two formats: ANALYZE (7.5) and MATLAB formats.
Analyze should be able to read in the data irrespective of computer platform. The MATLAB data was generated on Linux but can be read in by other *IX systems.
Explanation of MATLAB format
- mrinz - nonzero mri intensity voxel
- mannz - corresponding hand segmented voxel
- coord - voxel coordinate identifier
- ic - x coordinate: if ic value is zero set to xdim
- jc - y coordinate: if jc value is zero set to ydim
- kc - z coordinate: if kc value is zero set to zdim
- xdim, ydim, zdim - voxel resolution
Hand segmentation labels
- STG-GRAY = 1
- NOT-STG-GRAY = 0 (i.e. outside STG-GRAY).
This data is available with registered usernames and passwords. If you have already registered, and your registration has been confirmed, you may proceed to the download page.
Supported by
- NIH MH43775
- NIH MH60504
- NIH MH52886
- NIH P41-RR15241
- NSF NPACI